Doctors usually perform a prostate specific antigen (PSA) test to screen patients for prostate cancer. The PSA is a protein produced by prostate gland cells, and leaks into the bloodstream when the cancer attacks the normal structure of the prostate. A PSA test would therefore show positive for the cancer if it detects elevated levels of the protein in the blood.
But this test is not a perfect method, says Dr. Isares. “There are many other factors that could increase the PSA levels, and some of these causes are unknown. But at least we have a way to screen for prostate cancer.”
Treatment varies according to the development stage of the cancer and its aggressiveness, which is determined by the Gleason grading system. A higher Gleason score indicates a more aggressive cancer, and would require surgery or radiation therapy to treat the patient. Although these treatment options often yield successful results in treating prostate cancer, they could also lead to side effects in the patient including urinary incontinence, erectile dysfunction and bladder inflammation.
Dr. Isares recommends a new form of treatment that reduces the risk of side effects. High intensity focused ultrasound (HIFU) produces an ultrasound wave, about 10,000 times stronger than a normal ultrasound, directed at the prostate cancer cells, heating them up and killing them.
Because HIFU is controlled by a robotic arm and monitored real-time by doctors, Dr. Isares says that they are able to avoid other structures near the prostate like the bladder, the sphincter muscles that control continence and the nerves that control erection.