In the past, relieving the nerve pressure a standard carpal tunnel release treatment consisted of in-patient surgery with a long 3-5 cm wound incision. Because of the long incision and wide dissection, surgeries have to be operated under adequate general or regional anesthesia. The surgeries had wound complications such as wound dehiscence and painful scars. In 1988, Minimally Invasive Surgery (MIS) was introduced as a method to reduce these complications and it became more widespread in hospitals around the world. In 2008, a newly advanced technique – now widely known as the Wongsiri technique – became introduced in Minimally Invasive Surgery (MIS) medical reports. This new technique had superior outcome over open standard carpal tunnel release. Because of the key hole incision, less injury to the body is made when compared to open surgery. Most of the patients do not need general anesthesia, do not need to stay in hospital, and moreover, they experience early recovery within a few days at home with less wound pain. Another special tool (special thin visualization tube and special micro knife) is passed through the area and allow doctors to have a more specific view of the operating area and release specifically on the overly tight transverse carpal ligament. The goal of advanced MIS is to achieve a high level of success for complete release surgery, with more benefits for the patient and less downtime.