Patients should take one tablet per day after eating. Tablets should be taken at the same time each day and continued throughout the period for which patients are at risk of contracting the disease. Patients should begin taking the medication at least 7 days prior to the risk period and continue taking the drugs for at least 4 weeks subsequent to the end of the risk period.
Another schedule involves the taking of two tablets 2–4 hours prior to the risk period beginning, with a further two tablets to be taken later, one at 24 hours and one at 48 hours after the risk period ends. This method is referred to as on-demand PrEP and is not generally the standard practice involving these drugs.
PrEP medication should only be taken under the supervision of a medical professional as regular blood tests must be carried out. The patient must be monitored for the occurrence of negative side effects, including short-term symptoms such as dizziness and nausea, as well as long-term symptoms affecting bones and kidneys. Although PrEP is an effective way to protect a person from contracting the HIV virus, recipients should always be sure to wear condoms during sex since PrEP does not offer protection against other sexually transmitted diseases such as syphilis and gonorrhea.