The true cause of the condition remains unknown, but many doctors and experts in the field believe that it is linked to immune system abnormalities that cause an overproduction of white blood cells in the tissue walls of the digestive system which, in turn, lead to chronic inflammation and its complication such as perforation ,obstructions of digestive tract. That being said, genetics are also thought to play a crucial role, with the disease particularly common among those with a family history of the condition. People in this group are up to 20% more at risk of suffering from IBD than those without a family history of the condition.
Both Crohn’s disease and ulcerative colitis can occur in people of any age. However, Crohn’s disease is generally diagnosed between age 20-30, whereas ulcerative colitis is usually detected between age 15-35. Traditionally, westerners would be considered more susceptible to both conditions, but current trends show that the disease is on the rise among Thais and Asians owing to changing lifestyles and diets that mirror those found in the western world.